The HSBP1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HSBP1. This antibody recognizes Human, Mouse, and Rat antigen. The HSBP1 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Function: Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process.
Subunit Structure: Homohexamer. Associates with heptad repeats of HSF1 trimers and probably also HSF1 monomers, and with HSP70. Association with HSF1 trimers and HSP70 coincides with attenuation of heat shock response and the conversion of HSF1 trimer to monomer.
Similarity: Belongs to the HSBP1 family